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Research Article | Volume 4 Issue 4 (None, 2010) | Pages 57 - 59
Geographic tongue treated with topical tacrolimus
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Under a Creative Commons license
Open Access
PMID : PMC3157822
Received
Nov. 12, 2010
Published
Dec. 31, 2010
Abstract

Background:Geographic tongue, or benign migratory glossitis, is usually an asymptomatic inflammatory disorder of the tongue mucosa of unknown etiology. It is characterized by circinate, erythematous, ulcer-like lesions of the dorsum and lateral border of the tongue due to loss of filiform papillae of the tongue epithelium. Symptomatic treatments have not been evaluated rigorously.Main observation:We describe herein two cases of adult patients with persistent and painful geographic tongue successfully treated with topical application of 0.1% tacrolimus ointment.Conclusion:To our knowledge, this is the first report of successful treatment with topical 0.1% tacrolimus for symptomatic geographic tongue. Clinical trials are needed to confirm the efficacy and the safety of topical tacrolimus in treating geographic tongue.

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