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Research Article | Volume 6 Issue 2 (None, 2012) | Pages 52 - 53
Efficacy of 5% imiquimod cream in a patient with classic Kaposi sarcoma
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Under a Creative Commons license
Open Access
PMID : PMC3399677
Received
Nov. 4, 2011
Published
June 30, 2012
Abstract

Background:The classic Kaposi sarcoma is most common in the Mediterranean population over 50 years of age and presents with reddish-brown papules and nodules particularly on the lower limbs. Treatment depends on the clinical presentation and extension of lesions. Imiquimod is as an immune response modifier with antiangiogenic activity.Main observations:We present a 74-year-old man with classic Kaposi sarcoma who had multiple, small, violaceous papules and nodules on the trunk and extremities with a history of 14 years. He complained particularly from plantar hyperkeratotic painful nodules. Treatment with imiquimod 5% cream under occlusion resulted with almost complete regression within 12 weeks. No local or systemic side effects were observed.Conclusions:Topical imiquimod was a safe and effective therapy in our patient with classic Kaposi sarcoma.

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